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KMID : 0613820120220040478
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Journal of Life Science
2012 Volume.22 No. 4 p.478 ~ p.485
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Glasswort Powder Diet Activates Lipid Metabolism in Rat
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Seo Hyo-Bin
Kwak Yun-Young
Nam Ju-Ock
Song Young-Ju
Kim Byung-Oh
Ryu Sung-Pil
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Abstract
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The purpose of this study was to investigate the effects of glasswort powder intake on lipid metabolism. Rats were divided into three groups: a group fed a normal diet (CON), one fed a high fat diet (HFC), and one fed a high fat diet with glasswort powder (HFG). They were fed their respective diet for four weeks. Body weight was significantly lower (9%) in the HFG group than in the HFC group at the fourth week. According to the feces analysis, the HFG group showed the highest fat level (120% vs. CON; 138% vs. HFC) and fecal calories (110%). The concentration level of TG and LDL-C was 71.8% lower in the HFG group compared to the HFC group, while the concentration level of HDL-C was 152% higher in the HFG group. Expression of FABP in the liver was 197% greater in the HFG compared to the HFC group, with the expression of CPT-1 showing a similar tendency. These results suggest that glasswort powder intake suppresses weight gain and improves fat metabolism at the level of liver cells. From these results, we suggest that glasswort powder is effective against obesity by inhibiting the absorption of fat in the digestive tract.
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KEYWORD
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Glasswort, obesity, fecal calorie, FABP, CPT-1
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